STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02061Hypothetical protein; KEGG: eba:ebA6610 7.2e-05 dsbC; periplasmic thiol:disulfide interchange protein K03981; COG: COG1651 Protein-disulfide isomerase. (207 aa)    
Predicted Functional Partners:
CKO_02062
Hypothetical protein; KEGG: xcc:XCC0519 6.7e-56 dsbD; c-type cytochrome biogenesis protein K04084; COG: COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.979
CKO_02060
Hypothetical protein; KEGG: ngo:NGO2059 2.1e-09 putative peptide methionine sulfoxide reductase K07304:K07305; COG: COG0526 Thiol-disulfide isomerase and thioredoxins.
 
 
 0.920
dsbD
Hypothetical protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.758
dsbB
Hypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
 
 0.724
CKO_02064
Hypothetical protein; COG: NOG29928 non supervised orthologous group.
     
 0.699
cbpM
Hypothetical protein; Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.
 
     0.528
cbpA
Hypothetical protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
     
 0.493
CKO_02090
Hypothetical protein; KEGG: sec:SC2398 0. pgtB; phosphoglycerate transport: protein for signal transmission K08475; COG: COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.459
CKO_02065
Hypothetical protein.
       0.458
nqrC
Hypothetical protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
       0.428
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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