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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02105Hypothetical protein; KEGG: eci:UTI89_C1028 0. helD; DNA helicase IV K03658; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score:8.96. (684 aa)    
Predicted Functional Partners:
recC
Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]
  
 
 0.780
CKO_04651
Hypothetical protein; KEGG: shn:Shewana3_3435 8.8e-10 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.26; Belongs to the LysR transcriptional regulatory family.
  
    0.776
CKO_03401
Hypothetical protein; KEGG: ece:Z5988 8.8e-101 putative lipoate-protein ligase A K03800:K07186; COG: COG3726 Uncharacterized membrane protein affecting hemolysin expression.
  
     0.768
CKO_03421
Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
   
 0.767
CKO_03177
Hypothetical protein; COG: COG4568 Transcriptional antiterminator; Psort location: Cytoplasmic, score:8.96.
  
   
 0.760
ftsN
Hypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.758
CKO_00558
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
     0.753
CKO_00979
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
     0.744
CKO_01030
Hypothetical protein; COG: NOG13894 non supervised orthologous group.
  
     0.737
CKO_02137
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
     0.737
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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