close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sulAHypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa)    
Predicted Functional Partners:
ftsZ
Hypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.929
CKO_03675
Hypothetical protein; KEGG: rno:113960 5.0e-08 Cdc42bpb; Cdc42 binding protein kinase beta K08286; COG: COG3264 Small-conductance mechanosensitive channel; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.865
CKO_03938
Hypothetical protein; May be involved in recombinational repair of damaged DNA.
   
  
 0.856
CKO_01118
COG: COG3141 Uncharacterized protein conserved in bacteria.
   
    0.835
CKO_04897
COG: COG3714 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.753
CKO_00532
Hypothetical protein; COG: NOG08732 non supervised orthologous group.
  
     0.746
CKO_01989
Hypothetical protein; COG: COG3418 Flagellar biosynthesis/type III secretory pathway chaperone.
  
     0.745
CKO_04981
Hypothetical protein; KEGG: vfi:VFA0886 8.9e-26 zinc metalloprotease; COG: NOG14695 non supervised orthologous group.
  
     0.735
CKO_01842
Hypothetical protein; KEGG: sty:STY2206 1.2e-48 umuD; UmuD protein K03503; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Belongs to the peptidase S24 family.
  
  
 0.694
lexA
Hypothetical protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.694
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.