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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxKHypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa)    
Predicted Functional Partners:
CKO_05090
Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.998
lpxB
Hypothetical protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.993
kdsB
Hypothetical protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.967
kdsA
Hypothetical protein; KEGG: ecc:c1674 1.9e-144 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) K01627; COG: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Psort location: Cytoplasmic, score:8.96; Belongs to the KdsA family.
 
   
 0.931
pagP
Hypothetical protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
     
 0.920
msbA
Hypothetical protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
 
  
 0.896
CKO_04600
Hypothetical protein; KEGG: stm:STM3315 3.0e-162 yrbH; putative sugar phosphate isomerase K06041; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: Cytoplasmic, score:8.96.
 
   
 0.872
CKO_04062
Hypothetical protein; KEGG: eci:UTI89_C3070 4.2e-156 gutQ; GutQ protein K02467; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: Cytoplasmic, score:8.96.
 
   
 0.868
lpxC
Hypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.856
CKO_03185
Hypothetical protein; KEGG: ssn:SSO_0193 1.4e-77 lpxA; UDP-N-acetylglucosamine acetyltransferase; lipid A biosynthesis K00677; COG: COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Psort location: Cytoplasmic, score:9.97.
 
   
 0.853
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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