STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02184Hypothetical protein; KEGG: ecc:c1025 6.6e-167 trxB; thioredoxin reductase K00384; COG: COG0492 Thioredoxin reductase. (322 aa)    
Predicted Functional Partners:
CKO_00123
Hypothetical protein; KEGG: eci:UTI89_C4335 4.1e-55 trxA; thioredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score:9.26; Belongs to the thioredoxin family.
 
 0.991
CKO_02554
Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.932
CKO_02758
Hypothetical protein; KEGG: stm:STM0402 2.0e-101 putative thiol - alkyl hydroperoxide reductase K03386; COG: COG0450 Peroxiredoxin; Psort location: Cytoplasmic, score:9.97.
  
 
 0.932
selD
Hypothetical protein; Synthesizes selenophosphate from selenide and ATP.
     
 0.926
sufS
Hypothetical protein; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
 0.925
CKO_01707
Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97.
   
 
 0.910
CKO_04984
Hypothetical protein; KEGG: tde:TDE2200 6.7e-126 megL; methionine gamma-lyase K01761; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97.
   
 
 0.910
CKO_00202
Hypothetical protein; KEGG: ecp:ECP_2584 7.5e-72 thioredoxin 2 K03672; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score:9.97; Belongs to the thioredoxin family.
 
 0.908
CKO_01581
Hypothetical protein; KEGG: stm:STM1499 0. putative dimethyl sulphoxide reductase, chain A1 K07309; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.901
CKO_01582
Hypothetical protein; KEGG: stm:STM1498 0. putative dimethyl sulphoxide reductase K07310; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.901
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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