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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02209Hypothetical protein; KEGG: ecc:c1004 4.9e-297 poxB; pyruvate dehydrogenase K00156; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.96; Belongs to the TPP enzyme family. (572 aa)    
Predicted Functional Partners:
CKO_03300
Hypothetical protein; KEGG: eci:UTI89_C0086 3.5e-81 ilvH; acetolactate synthase III, valine sensitive, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.96.
 
 0.986
CKO_00011
Hypothetical protein; KEGG: sty:STY3987 7.8e-45 ilvN; acetolactate synthase small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.96.
  
 0.978
CKO_01425
Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
  
 
 0.950
CKO_00332
Hypothetical protein; KEGG: sty:STY2709 0. maeB; NADP-dependent malate dehydrogenase (decarboxylating) K00029; COG: COG0280 Phosphotransacetylase.
  
 
 0.944
lldD
Hypothetical protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 
 0.930
leuA
Hypothetical protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.926
leuD
Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.926
CKO_01429
Hypothetical protein; KEGG: spt:SPA1239 2.2e-168 ldhA; D-lactate dehydrogenase K03778; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.923
CKO_01725
Hypothetical protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.922
leuC
Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.920
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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