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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolBHypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (431 aa)    
Predicted Functional Partners:
pal
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 0.996
tolR
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
 0.969
tolQ
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
  
 0.963
cpoB
Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.939
CKO_04401
Hypothetical protein; COG: COG0811 Biopolymer transport proteins; Psort location: CytoplasmicMembrane, score:10.00.
 
  
 0.858
CKO_02111
Hypothetical protein; KEGG: bte:BTH_I0426 9.3e-06 cytochrome c oxidase, subunit II K02275; COG: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Psort location: OuterMembrane, score:10.00; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.852
CKO_02137
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
 
 
 0.839
CKO_00558
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
 
 
 0.834
CKO_02401
Hypothetical protein; KEGG: eci:UTI89_C0735 7.2e-58 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02.
 
 
 0.806
surA
Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
  
  
 0.799
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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