Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_02401Hypothetical protein; KEGG: eci:UTI89_C0735 7.2e-58 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02. (124 aa)    
Predicted Functional Partners:
CKO_02402
Hypothetical protein; KEGG: eci:UTI89_C0735 1.0e-83 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02.
     0.979
tolB
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
   0.795
CKO_01694
Hypothetical protein; Psort location: Cytoplasmic, score:8.96.
  
 
 
 0.766
CKO_02137
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
 
   0.754
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.754
CKO_00558
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
 
   0.741
lapA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.721
CKO_01332
Hypothetical protein; COG: NOG06197 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.711
CKO_01613
Hypothetical protein; COG: NOG06063 non supervised orthologous group.
  
     0.709
tolR
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.705
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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