Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_02402Hypothetical protein; KEGG: eci:UTI89_C0735 1.0e-83 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02. (250 aa)    
Predicted Functional Partners:
CKO_02401
Hypothetical protein; KEGG: eci:UTI89_C0735 7.2e-58 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02.
     0.979
tolR
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.794
CKO_02406
COG: COG3790 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.46.
 
     0.775
CKO_00447
COG: COG3691 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
     0.765
tolQ
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
 
 0.721
wzyE
Hypothetical protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.
  
     0.712
CKO_02727
COG: COG3056 Uncharacterized lipoprotein.
  
     0.698
CKO_03087
Hypothetical protein; COG: COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; Psort location: Periplasmic, score:10.00.
  
     0.697
tolB
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
   0.693
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.693
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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