Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_02405Hypothetical protein; KEGG: eci:UTI89_C0732 5.9e-63 ybgC; cytoplasmic Tol-Pal protein; COG: COG0824 Predicted thioesterase. (132 aa)    
Predicted Functional Partners:
tolQ
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
  
 0.949
tolR
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
  
 0.905
secA
Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
   
   0.703
CKO_02402
Hypothetical protein; KEGG: eci:UTI89_C0735 1.0e-83 tolA; membrane spanning protein TolA K03646; COG: COG3064 Membrane protein involved in colicin uptake; Psort location: CytoplasmicMembrane, score:8.02.
 
     0.692
tolB
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
  
 0.666
CKO_04401
Hypothetical protein; COG: COG0811 Biopolymer transport proteins; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.642
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.627
CKO_00874
Hypothetical protein; KEGG: ava:Ava_4834 1.6e-101 beta-ketoacyl synthase K01845; COG: COG3321 Polyketide synthase modules and related proteins; Psort location: Cytoplasmic, score:9.26.
   
  
 0.604
CKO_02406
COG: COG3790 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.46.
     
 0.595
pal
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
  
 0.572
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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