Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pxpAHypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (244 aa)    
Predicted Functional Partners:
CKO_02456
Hypothetical protein; KEGG: eci:UTI89_C0710 1.1e-148 ybgK; hypothetical protein K01941; COG: COG1984 Allophanate hydrolase subunit 2; Psort location: Cytoplasmic, score:8.96.
 
 0.999
CKO_02457
Hypothetical protein; KEGG: eci:UTI89_C0709 7.1e-99 ybgJ; hypothetical protein YbgJ K01457; COG: COG2049 Allophanate hydrolase subunit 1.
 
 0.999
CKO_00830
Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
     
  0.900
CKO_01283
Hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
CKO_02585
Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
     
  0.900
gshA
Hypothetical protein; KEGG: spt:SPA2677 1.2e-270 gshA; gamma-glutamylcysteine synthetase K01919; COG: COG2918 Gamma-glutamylcysteine synthetase; Psort location: Cytoplasmic, score:8.96; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
CKO_04868
Hypothetical protein; KEGG: sec:SC3480 8.2e-295 ggt; gamma-glutamyltranspeptidase K00681; COG: COG0405 Gamma-glutamyltransferase; Psort location: Periplasmic, score:10.00.
     
  0.900
nei
Hypothetical protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
    
 0.865
CKO_03140
Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97.
   
 
  0.804
CKO_01789
Hypothetical protein; KEGG: spt:SPA1545 3.0e-235 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score:9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
  0.802
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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