Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
CKO_02466Hypothetical protein; KEGG: eco:b0695 0. kdpD, kac; sensor for high-affinity potassium transport system K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score:9.99. (895 aa)    
Predicted Functional Partners:
CKO_02467
Hypothetical protein; KEGG: eci:UTI89_C0698 1.9e-105 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score:9.97.
 
 0.999
kdpC
Hypothetical protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.992
kdpB
Hypothetical protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.975
kdpA
Hypothetical protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.968
CKO_04614
Hypothetical protein; KEGG: sec:SC3266 0. arcB; aerobic respiration control sensor protein K07648; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.97.
  
 
 0.882
CKO_00702
Hypothetical protein; KEGG: eci:UTI89_C2354 1.7e-122 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score:9.97.
  
 
 0.717
CKO_04139
Hypothetical protein; KEGG: spt:SPA2823 0. barA; sensor protein; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.99.
   
 
 0.656
CKO_04368
Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82.
   
 
 0.607
CKO_02462
Hypothetical protein; Psort location: Cytoplasmic, score:8.96.
       0.604
CKO_03790
Hypothetical protein; KEGG: psp:PSPPH_3276 1.4e-71 sensory box sensor histidine kinase/response regulator; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:10.00.
   
 
 0.598
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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