Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CKO_02479Hypothetical protein; KEGG: psp:PSPPH_3782 8.6e-14 porin D; COG: NOG06287 non supervised orthologous group; Psort location: OuterMembrane, score:9.49. (468 aa)    
Predicted Functional Partners:
CKO_02480
Hypothetical protein.
       0.773
CKO_01428
Hypothetical protein; KEGG: pmu:PM0180 0.0081 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790; COG: COG3187 Heat shock protein.
  
     0.731
CKO_03176
Hypothetical protein; COG: NOG13866 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0253 family.
  
     0.714
sbmC
Hypothetical protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
  
     0.687
CKO_02478
Hypothetical protein; COG: NOG11319 non supervised orthologous group.
     
 0.678
sulA
Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.600
CKO_02033
Hypothetical protein; COG: NOG09737 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.46.
  
     0.589
mdtH
Hypothetical protein; KEGG: gsu:GSU3029 0.00067 long-chain-fatty-acid--[acyl-carrier-protein] ligase / acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase K05939:K01909; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.578
CKO_04894
COG: COG3776 Predicted membrane protein.
  
     0.567
lamB
Hypothetical protein; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.
  
  
 0.562
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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