| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00038 | cpoB | CKO_00038 | CKO_02398 | Hypothetical protein; KEGG: eci:UTI89_C4240 9.5e-191 yidR; hypothetical protein YidR; COG: NOG06296 non supervised orthologous group. | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.835 |
| CKO_00038 | rlpA | CKO_00038 | CKO_02524 | Hypothetical protein; KEGG: eci:UTI89_C4240 9.5e-191 yidR; hypothetical protein YidR; COG: NOG06296 non supervised orthologous group. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.576 |
| CKO_01197 | CKO_02526 | CKO_01197 | CKO_02526 | Hypothetical protein; KEGG: ecc:c1641 1.0e-131 ldcA; muramoyltetrapeptide carboxypeptidase K01297; COG: COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.545 |
| CKO_01197 | rlpA | CKO_01197 | CKO_02524 | Hypothetical protein; KEGG: ecc:c1641 1.0e-131 ldcA; muramoyltetrapeptide carboxypeptidase K01297; COG: COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.520 |
| CKO_01425 | rlpA | CKO_01425 | CKO_02524 | Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.780 |
| CKO_02526 | CKO_01197 | CKO_02526 | CKO_01197 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; KEGG: ecc:c1641 1.0e-131 ldcA; muramoyltetrapeptide carboxypeptidase K01297; COG: COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. | 0.545 |
| CKO_02526 | mrdA-2 | CKO_02526 | CKO_02522 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.724 |
| CKO_02526 | mrdB | CKO_02526 | CKO_02523 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.660 |
| CKO_02526 | rlmH | CKO_02526 | CKO_02521 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.672 |
| CKO_02526 | rlpA | CKO_02526 | CKO_02524 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.582 |
| CKO_02526 | rsfS | CKO_02526 | CKO_02520 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.498 |
| CKO_02526 | tolB | CKO_02526 | CKO_02400 | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.495 |
| cpoB | CKO_00038 | CKO_02398 | CKO_00038 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Hypothetical protein; KEGG: eci:UTI89_C4240 9.5e-191 yidR; hypothetical protein YidR; COG: NOG06296 non supervised orthologous group. | 0.835 |
| cpoB | rlpA | CKO_02398 | CKO_02524 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.549 |
| cpoB | tolB | CKO_02398 | CKO_02400 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.939 |
| mrdA-2 | CKO_02526 | CKO_02522 | CKO_02526 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.724 |
| mrdA-2 | mrdB | CKO_02522 | CKO_02523 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Hypothetical protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.992 |
| mrdA-2 | rlmH | CKO_02522 | CKO_02521 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.814 |
| mrdA-2 | rlpA | CKO_02522 | CKO_02524 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.843 |
| mrdA-2 | rsfS | CKO_02522 | CKO_02520 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.722 |