| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00208 | CKO_02532 | CKO_00208 | CKO_02532 | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.414 |
| CKO_00208 | birA | CKO_00208 | CKO_03018 | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.488 |
| CKO_01596 | CKO_02532 | CKO_01596 | CKO_02532 | Hypothetical protein; KEGG: shn:Shewana3_1692 3.5e-49 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.453 |
| CKO_01789 | CKO_02532 | CKO_01789 | CKO_02532 | Hypothetical protein; KEGG: spt:SPA1545 3.0e-235 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score:9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.429 |
| CKO_02532 | CKO_00208 | CKO_02532 | CKO_00208 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.414 |
| CKO_02532 | CKO_01596 | CKO_02532 | CKO_01596 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: shn:Shewana3_1692 3.5e-49 Xaa-His dipeptidase K01270; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00. | 0.453 |
| CKO_02532 | CKO_01789 | CKO_02532 | CKO_01789 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: spt:SPA1545 3.0e-235 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score:9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.429 |
| CKO_02532 | CKO_04009 | CKO_02532 | CKO_04009 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.473 |
| CKO_02532 | birA | CKO_02532 | CKO_03018 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.412 |
| CKO_02532 | crcB | CKO_02532 | CKO_02533 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.523 |
| CKO_02532 | guaA | CKO_02532 | CKO_00280 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.467 |
| CKO_02532 | norW | CKO_02532 | CKO_04065 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase. | 0.436 |
| CKO_02532 | purL | CKO_02532 | CKO_00226 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.450 |
| CKO_02532 | tatE | CKO_02532 | CKO_02531 | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.549 |
| CKO_04009 | CKO_02532 | CKO_04009 | CKO_02532 | Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.473 |
| birA | CKO_00208 | CKO_03018 | CKO_00208 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.488 |
| birA | CKO_02532 | CKO_03018 | CKO_02532 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.412 |
| birA | guaA | CKO_03018 | CKO_00280 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.538 |
| crcB | CKO_02532 | CKO_02533 | CKO_02532 | Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Hypothetical protein; KEGG: eci:UTI89_C0629 1.2e-112 ybeM; putative amidase K01501; COG: COG0388 Predicted amidohydrolase; Psort location: Cytoplasmic, score:8.96. | 0.523 |
| crcB | tatE | CKO_02533 | CKO_02531 | Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.481 |