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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02554Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)    
Predicted Functional Partners:
CKO_02552
Hypothetical protein; KEGG: eco:b0606 2.1e-266 ahpF; alkyl hydroperoxide reductase subunit, FAD/NAD(P)-binding, detoxification of hydroperoxides K03387; COG: COG3634 Alkyl hydroperoxide reductase, large subunit; Psort location: Cytoplasmic, score:9.97.
 
  
 0.973
CKO_02184
Hypothetical protein; KEGG: ecc:c1025 6.6e-167 trxB; thioredoxin reductase K00384; COG: COG0492 Thioredoxin reductase.
  
 
 0.932
CKO_00531
Hypothetical protein; KEGG: ypk:y2981 5.4e-227 katE; catalase; hydroperoxidase HPII(III) K03781; COG: COG0753 Catalase; Psort location: Cytoplasmic, score:9.26; Belongs to the catalase family.
  
 
 0.854
CKO_00582
KEGG: azo:azo3929 3.3e-30 ccmG; protein disulfide-isomerase K01829; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Periplasmic, score:9.76.
  
 0.817
CKO_02051
Hypothetical protein; KEGG: reh:H16_A0306 5.1e-09 bcp; peroxiredoxin K00435; COG: COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.817
CKO_02060
Hypothetical protein; KEGG: ngo:NGO2059 2.1e-09 putative peptide methionine sulfoxide reductase K07304:K07305; COG: COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.817
fur
Hypothetical protein; COG: COG0735 Fe2+/Zn2+ uptake regulation proteins; Psort location: Cytoplasmic, score:9.97; Belongs to the Fur family.
  
  
 0.734
dps
Hypothetical protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
  
  
 0.730
CKO_02938
Hypothetical protein; COG: NOG11865 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
    0.662
grpE
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
   
 
 0.623
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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