close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02568Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. (391 aa)    
Predicted Functional Partners:
CKO_02566
Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96.
 
 
 0.999
CKO_02567
Hypothetical protein; KEGG: eci:UTI89_C0596 6.5e-263 entE; enterobactin synthetase component E K02363; COG: COG1021 Peptide arylation enzymes; Psort location: Cytoplasmic, score:9.97.
 
  
 0.994
CKO_02565
Hypothetical protein; KEGG: stm:STM0598 1.8e-118 entA; 2,3-dihydroxybenzoate-2,3-dehydrogenase K00216; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score:9.26.
 
  
 0.989
menD
Hypothetical protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
 0.982
CKO_02575
Hypothetical protein; KEGG: stm:STM0588 0. entF; enterobactin synthetase, component F (nonribosomal peptide synthetase) K02364; COG: COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases; Psort location: CytoplasmicMembrane, score:8.46.
 
  
 0.980
entH
Hypothetical protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family.
 
  
 0.965
CKO_02569
Hypothetical protein; COG: COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component; Psort location: Periplasmic, score:9.76.
 
  
 0.945
trpD
Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.931
CKO_00916
Hypothetical protein; KEGG: eci:UTI89_C2178 7.5e-230 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96.
  
  
0.930
CKO_01253
Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96.
  
  
0.930
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (24%) [HD]