close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02663Hypothetical protein; KEGG: tfu:Tfu_2581 1.5e-32 inosine-uridine preferring nucleoside hydrolase K01239; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family. (339 aa)    
Predicted Functional Partners:
CKO_02662
Hypothetical protein; KEGG: msm:MSMEG_3095 0.0013 D-ribose-binding periplasmic protein; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score:9.97.
       0.799
rbsK
Hypothetical protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.692
CKO_02664
Hypothetical protein; KEGG: oih:OB0089 2.7e-28 cation-transporting ATPase K07507; COG: COG1285 Uncharacterized membrane protein; Psort location: CytoplasmicMembrane, score:9.46.
       0.626
CKO_02661
Hypothetical protein; KEGG: cal:orf19.2425 5.6e-07 highly conserved hypothetical protein K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
  
 0.547
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.460
CKO_00616
Hypothetical protein; KEGG: eci:UTI89_C2435 4.4e-58 yeiI; hypothetical sugar kinase YeiI K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.26.
 
  
 0.453
CKO_03130
Hypothetical protein; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.448
CKO_02665
Hypothetical protein; KEGG: sty:STY0544 0. ybaR; copper-transporting ATPase K01533; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score:10.00.
  
    0.426
CKO_00624
Hypothetical protein; KEGG: eci:UTI89_C2435 5.2e-167 yeiI; hypothetical sugar kinase YeiI K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.97.
 
  
 0.413
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (50%) [HD]