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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02736Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa)    
Predicted Functional Partners:
panB
Hypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.944
panC
Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.937
CKO_00562
Hypothetical protein; COG: COG3145 Alkylated DNA repair protein.
   
    0.819
CKO_02737
Hypothetical protein; KEGG: eci:UTI89_C0447 2.6e-94 thiJ; 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme K03152; COG: COG0693 Putative intracellular protease/amidase.
       0.800
CKO_01575
Hypothetical protein; KEGG: eci:UTI89_C1768 8.7e-220 rspA; starvation sensing protein RspA K08323; COG: COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Psort location: Cytoplasmic, score:8.96.
   
    0.612
CKO_02735
COG: COG1666 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0234 family.
       0.590
CKO_05096
Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.475
birA
Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.416
panD
Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.401
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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