STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acpHHypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. (211 aa)    
Predicted Functional Partners:
coaA
Hypothetical protein; KEGG: ecc:c4933 2.6e-165 coaA; pantothenate kinase K00867; COG: COG1072 Panthothenate kinase.
     
 0.912
acpS
Hypothetical protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
     
 0.906
coaD
Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.903
CKO_00857
Hypothetical protein; KEGG: syn:slr0495 6.5e-18 lipopeptide antibiotics iturin a biosynthesis protein K01005; COG: COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
     
  0.900
CKO_04136
Hypothetical protein; KEGG: pha:PSHAa0740 1.5e-59 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; COG: COG1694 Predicted pyrophosphatase; Psort location: Cytoplasmic, score:8.96.
     
  0.900
CKO_04925
Hypothetical protein; KEGG: sty:STY4228 1.1e-84 4'-phosphopantetheinyl transferase K06133; COG: COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
     
  0.900
CKO_05096
Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
     
  0.900
queA
Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
       0.563
CKO_02758
Hypothetical protein; KEGG: stm:STM0402 2.0e-101 putative thiol - alkyl hydroperoxide reductase K03386; COG: COG0450 Peroxiredoxin; Psort location: Cytoplasmic, score:9.97.
       0.537
tgt
Hypothetical protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...]
       0.424
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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