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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02827KEGG: spt:SPA2352 0. prpE; PrpE protein K01908; COG: COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; Psort location: Cytoplasmic, score:9.26. (628 aa)    
Predicted Functional Partners:
CKO_02829
Hypothetical protein; KEGG: ecp:ECP_0408 9.0e-202 2-methylcitrate synthase K01659; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
 
 0.990
fadB
Hypothetical protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.976
fadJ
Hypothetical protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.976
CKO_00497
Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.939
CKO_03994
Hypothetical protein; KEGG: ype:YPO2577 4.2e-236 putative methylmalonate-semialdehyde dehydrogenase K00140; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26.
   
 0.932
CKO_00785
Hypothetical protein; KEGG: rru:Rru_A0914 1.9e-112 aldehyde dehydrogenase K04021; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: OuterMembrane, score:9.96.
   
 0.931
ackA
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.922
pduW
Hypothetical protein; KEGG: stm:STM2057 1.5e-183 pduW; Propanediol utilization: propionate kinase K00932; COG: COG0282 Acetate kinase; Psort location: Cytoplasmic, score:9.97.
   
 
 0.922
tdcD
Hypothetical protein; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
   
 
 0.922
acs
Hypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
  
 
0.912
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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