close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabRHypothetical protein; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (210 aa)    
Predicted Functional Partners:
CKO_03028
Hypothetical protein; COG: NOG10261 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.50.
  
    0.806
metJ
Hypothetical protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.778
plsB
Hypothetical protein; KEGG: sdy:SDY_4533 0. plsB; glycerol-3-phosphate acyltransferase K00631; COG: COG2937 Glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family.
  
   
 0.774
fadR
Hypothetical protein; Multifunctional regulator of fatty acid metabolism.
  
  
 0.742
seqA
Hypothetical protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
   
 0.717
argR-2
Hypothetical protein; Regulates arginine biosynthesis genes.
  
  
 0.674
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.664
CKO_00587
COG: COG3082 Uncharacterized protein conserved in bacteria; Belongs to the UPF0352 family.
  
     0.649
CKO_04561
Hypothetical protein; May be involved in cell division.
  
     0.649
CKO_03027
Hypothetical protein.
       0.629
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.