| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00467 | CKO_03054 | CKO_00467 | CKO_03054 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.970 |
| CKO_00467 | CKO_03383 | CKO_00467 | CKO_03383 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; KEGG: sbo:SBO_0003 1.6e-213 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score:8.96. | 0.577 |
| CKO_00467 | CKO_03385 | CKO_00467 | CKO_03385 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; KEGG: sec:SC0002 0. thrA; aspartokinase I K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.963 |
| CKO_00467 | CKO_03902 | CKO_00467 | CKO_03902 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.467 |
| CKO_00467 | dapA | CKO_00467 | CKO_00309 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.825 |
| CKO_00467 | thrB | CKO_00467 | CKO_03384 | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.548 |
| CKO_01707 | CKO_03054 | CKO_01707 | CKO_03054 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.960 |
| CKO_01707 | CKO_03055 | CKO_01707 | CKO_03055 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: eco:b3939 2.8e-198 metB, met-1, met1; cystathionine gamma-synthase K01739; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | 0.909 |
| CKO_01707 | CKO_03385 | CKO_01707 | CKO_03385 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: sec:SC0002 0. thrA; aspartokinase I K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.935 |
| CKO_01707 | CKO_03902 | CKO_01707 | CKO_03902 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
| CKO_01707 | metAS | CKO_01707 | CKO_03907 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.785 |
| CKO_01707 | thrB | CKO_01707 | CKO_03384 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.850 |
| CKO_03054 | CKO_00467 | CKO_03054 | CKO_00467 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; KEGG: eci:UTI89_C2604 2.8e-159 usg; USG-1 protein K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.970 |
| CKO_03054 | CKO_01707 | CKO_03054 | CKO_01707 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | 0.960 |
| CKO_03054 | CKO_03055 | CKO_03054 | CKO_03055 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; KEGG: eco:b3939 2.8e-198 metB, met-1, met1; cystathionine gamma-synthase K01739; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. | 0.990 |
| CKO_03054 | CKO_03383 | CKO_03054 | CKO_03383 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; KEGG: sbo:SBO_0003 1.6e-213 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score:8.96. | 0.987 |
| CKO_03054 | CKO_03385 | CKO_03054 | CKO_03385 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; KEGG: sec:SC0002 0. thrA; aspartokinase I K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.991 |
| CKO_03054 | CKO_03902 | CKO_03054 | CKO_03902 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.969 |
| CKO_03054 | asd | CKO_03054 | CKO_04853 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.992 |
| CKO_03054 | dapA | CKO_03054 | CKO_00309 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.959 |