Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (440 aa)    
Predicted Functional Partners:
pth
Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
  
 0.798
truB
Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.706
truA
Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.701
CKO_03179
KEGG: stt:t0237 2.9e-61 hypothetical protein K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
       0.681
rplO
Hypothetical protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   
 0.665
CKO_03191
Hypothetical protein; KEGG: ecj:JW5810 2.5e-151 cdsA; CDP-diglyceride synthase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score:10.00.
 
     0.653
CKO_01173
KEGG: ecp:ECP_1750 1.3e-108 hypothetical protease YeaZ K01423; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Extracellular, score:9.71.
 
   
 0.646
rpoA
Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.643
mfd
Hypothetical protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
    0.641
metG
Hypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.632
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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