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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btuFHypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa)    
Predicted Functional Partners:
btuC
Hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
 
 
 0.994
btuD
Hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
  
 
 0.913
mtnN
Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
  
  
 0.820
CKO_02659
Hypothetical protein; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.795
hmuV-2
Hypothetical protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
 
 0.794
CKO_03742
Hypothetical protein; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.793
CKO_03210
COG: COG2860 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:10.00.
     
 0.755
CKO_00921
Hypothetical protein; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.751
CKO_00852
Hypothetical protein; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.747
CKO_00832
Hypothetical protein; KEGG: tbd:Tbd_2559 0.0074 dsbD; thiol:disulfide interchange protein DsbD K04084; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.734
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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