CKO_03220 protein (Citrobacter koseri) - STRING interaction network

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CKO_03220

Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (846 aa)

Predicted Functional Partners:

CKO_04819

0.956

ftsI-2

0.920

CKO_00263

0.913

ftsI

0.909

ftsN

0.862

lpoB

0.818

mrdA-2

0.776

mrdA

0.756

CKO_02181

0.749

mrdB

0.666

Your Current Organism:

Citrobacter koseri

NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKO_00263	CKO_03220	CKO_00263	CKO_03220	Hypothetical protein; KEGG: ecc:c3042 0. pbpC; penicillin-binding protein 1C K05367; COG: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.913
CKO_00263	CKO_04819	CKO_00263	CKO_04819	Hypothetical protein; KEGG: ecc:c3042 0. pbpC; penicillin-binding protein 1C K05367; COG: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; KEGG: stm:STM3493 0. mrcA; transpeptidase of penicillin-binding protein 1a (peptidoglycan synthetase) K05366; COG: COG5009 Membrane carboxypeptidase/penicillin-binding protein.	0.922
CKO_02181	CKO_03220	CKO_02181	CKO_03220	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.749
CKO_02181	CKO_04819	CKO_02181	CKO_04819	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; KEGG: stm:STM3493 0. mrcA; transpeptidase of penicillin-binding protein 1a (peptidoglycan synthetase) K05366; COG: COG5009 Membrane carboxypeptidase/penicillin-binding protein.	0.501
CKO_02181	ftsI	CKO_02181	CKO_01154	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.793
CKO_02181	ftsI-2	CKO_02181	CKO_03291	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.798
CKO_02181	mrdA	CKO_02181	CKO_01083	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.748
CKO_02181	mrdA-2	CKO_02181	CKO_02522	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.748
CKO_02181	mrdB	CKO_02181	CKO_02523	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	Hypothetical protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.686
CKO_03220	CKO_00263	CKO_03220	CKO_00263	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; KEGG: ecc:c3042 0. pbpC; penicillin-binding protein 1C K05367; COG: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; Psort location: CytoplasmicMembrane, score:10.00.	0.913
CKO_03220	CKO_02181	CKO_03220	CKO_02181	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; KEGG: pen:PSEEN2212 1.5e-185 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:10.00.	0.749
CKO_03220	CKO_04819	CKO_03220	CKO_04819	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; KEGG: stm:STM3493 0. mrcA; transpeptidase of penicillin-binding protein 1a (peptidoglycan synthetase) K05366; COG: COG5009 Membrane carboxypeptidase/penicillin-binding protein.	0.956
CKO_03220	ftsI	CKO_03220	CKO_01154	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.909
CKO_03220	ftsI-2	CKO_03220	CKO_03291	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.920
CKO_03220	ftsN	CKO_03220	CKO_03061	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.	0.862
CKO_03220	lpoB	CKO_03220	CKO_01951	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).	0.818
CKO_03220	mrdA	CKO_03220	CKO_01083	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.756
CKO_03220	mrdA-2	CKO_03220	CKO_02522	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.776
CKO_03220	mrdB	CKO_03220	CKO_02523	Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.666
CKO_04819	CKO_00263	CKO_04819	CKO_00263	Hypothetical protein; KEGG: stm:STM3493 0. mrcA; transpeptidase of penicillin-binding protein 1a (peptidoglycan synthetase) K05366; COG: COG5009 Membrane carboxypeptidase/penicillin-binding protein.	Hypothetical protein; KEGG: ecc:c3042 0. pbpC; penicillin-binding protein 1C K05367; COG: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; Psort location: CytoplasmicMembrane, score:10.00.	0.922

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