| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_03221 | CKO_03222 | CKO_03221 | CKO_03222 | Hypothetical protein; KEGG: eci:UTI89_C0162 0. hrpB; ATP-dependent helicase HrpB K03579; COG: COG1643 HrpA-like helicases. | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.613 |
| CKO_03221 | sfsA | CKO_03221 | CKO_03223 | Hypothetical protein; KEGG: eci:UTI89_C0162 0. hrpB; ATP-dependent helicase HrpB K03579; COG: COG1643 HrpA-like helicases. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.550 |
| CKO_03222 | CKO_03221 | CKO_03222 | CKO_03221 | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Hypothetical protein; KEGG: eci:UTI89_C0162 0. hrpB; ATP-dependent helicase HrpB K03579; COG: COG1643 HrpA-like helicases. | 0.613 |
| CKO_03222 | dksA | CKO_03222 | CKO_03224 | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.415 |
| CKO_03222 | sfsA | CKO_03222 | CKO_03223 | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.711 |
| CKO_04336 | sfsA | CKO_04336 | CKO_03223 | Hypothetical protein; Adenine glycosylase active on G-A mispairs. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.883 |
| dksA | CKO_03222 | CKO_03224 | CKO_03222 | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.415 |
| dksA | gluQ | CKO_03224 | CKO_03225 | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Hypothetical protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.632 |
| dksA | sfsA | CKO_03224 | CKO_03223 | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.630 |
| gluQ | dksA | CKO_03225 | CKO_03224 | Hypothetical protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.632 |
| gluQ | sfsA | CKO_03225 | CKO_03223 | Hypothetical protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.526 |
| proA | sfsA | CKO_02952 | CKO_03223 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | 0.617 |
| sfsA | CKO_03221 | CKO_03223 | CKO_03221 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; KEGG: eci:UTI89_C0162 0. hrpB; ATP-dependent helicase HrpB K03579; COG: COG1643 HrpA-like helicases. | 0.550 |
| sfsA | CKO_03222 | CKO_03223 | CKO_03222 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.711 |
| sfsA | CKO_04336 | CKO_03223 | CKO_04336 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; Adenine glycosylase active on G-A mispairs. | 0.883 |
| sfsA | dksA | CKO_03223 | CKO_03224 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.630 |
| sfsA | gluQ | CKO_03223 | CKO_03225 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.526 |
| sfsA | proA | CKO_03223 | CKO_02952 | COG: COG1489 DNA-binding protein, stimulates sugar fermentation; Psort location: Cytoplasmic, score:8.96; Belongs to the SfsA family. | Hypothetical protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.617 |