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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speEHypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (288 aa)    
Predicted Functional Partners:
speD
Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
 
 
 0.999
speB
Hypothetical protein; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
 
 
 0.955
CKO_02469
Hypothetical protein; KEGG: ssn:SSO_0644 0. speF; ornithine decarboxylase isozyme, inducible K01581; COG: COG1982 Arginine/lysine/ornithine decarboxylases.
  
 
 0.931
CKO_04340
Hypothetical protein; KEGG: stm:STM3114 0. speC; ornithine decarboxylase isozyme K01581; COG: COG1982 Arginine/lysine/ornithine decarboxylases.
  
 
 0.931
CKO_01578
Hypothetical protein; KEGG: sec:SC1519 1.5e-91 speG; spermidine N1-acetyltransferase K00657; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: Cytoplasmic, score:8.96.
     
 0.922
patA
Hypothetical protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
     
 0.920
CKO_04379
Hypothetical protein; KEGG: stt:t3060 0. gsp; glutathionylspermidine synthetase/amidase K01460:K01917; COG: COG0754 Glutathionylspermidine synthase; Psort location: Cytoplasmic, score:8.96.
    
  0.905
mtnN
Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
    
 0.901
CKO_03245
Hypothetical protein; COG: NOG09835 non supervised orthologous group.
     0.848
CKO_03246
Hypothetical protein.
       0.773
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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