Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CKO_03260Hypothetical protein; KEGG: btk:BT9727_3817 4.4e-07 transcriptional regulator, GntR family K07979; COG: COG2186 Transcriptional regulators; Psort location: Cytoplasmic, score:8.96. (254 aa)    
Predicted Functional Partners:
CKO_03259
Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.696
CKO_05059
Hypothetical protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.657
CKO_04243
Hypothetical protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.641
CKO_03396
Hypothetical protein; KEGG: stm:STM4580.S 1.5e-217 nadR; nicotinamide-nucleotide adenylyltransferase K00952:K06210:K06211; COG: COG3172 Predicted ATPase/kinase involved in NAD metabolism; Psort location: Cytoplasmic, score:8.96.
   
  
 0.620
CKO_02415
Hypothetical protein; KEGG: btk:BT9727_3183 4.3e-21 transcriptional regulator, GntR family; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score:8.96.
  
    0.552
lldD
Hypothetical protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
  
 0.530
CKO_04011
Hypothetical protein; KEGG: msm:MSMEG_3400 4.3e-06 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators.
  
  
 0.528
fadR
Hypothetical protein; Multifunctional regulator of fatty acid metabolism.
  
   
 0.462
CKO_03846
Hypothetical protein; KEGG: bps:BPSL0426 6.5e-89 dctB; C4-dicarboxylate transport sensor protein; COG: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; Psort location: CytoplasmicMembrane, score:9.82.
 
     0.454
sthA
Hypothetical protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.443
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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