| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00208 | CKO_03267 | CKO_00208 | CKO_03267 | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | 0.996 |
| CKO_00208 | CKO_03396 | CKO_00208 | CKO_03396 | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Hypothetical protein; KEGG: stm:STM4580.S 1.5e-217 nadR; nicotinamide-nucleotide adenylyltransferase K00952:K06210:K06211; COG: COG3172 Predicted ATPase/kinase involved in NAD metabolism; Psort location: Cytoplasmic, score:8.96. | 0.416 |
| CKO_00208 | nadA | CKO_00208 | CKO_02390 | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Hypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.999 |
| CKO_02669 | CKO_03267 | CKO_02669 | CKO_03267 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | 0.900 |
| CKO_02669 | CKO_03396 | CKO_02669 | CKO_03396 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; KEGG: stm:STM4580.S 1.5e-217 nadR; nicotinamide-nucleotide adenylyltransferase K00952:K06210:K06211; COG: COG3172 Predicted ATPase/kinase involved in NAD metabolism; Psort location: Cytoplasmic, score:8.96. | 0.924 |
| CKO_02669 | CKO_04051 | CKO_02669 | CKO_04051 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.904 |
| CKO_02669 | CKO_04136 | CKO_02669 | CKO_04136 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; KEGG: pha:PSHAa0740 1.5e-59 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; COG: COG1694 Predicted pyrophosphatase; Psort location: Cytoplasmic, score:8.96. | 0.903 |
| CKO_02669 | nadD | CKO_02669 | CKO_02517 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
| CKO_02669 | nudC | CKO_02669 | CKO_02990 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; KEGG: ssn:SSO_4169 1.2e-135 yjaD; hypothetical protein K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score:8.96. | 0.910 |
| CKO_02669 | pncB | CKO_02669 | CKO_02134 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.906 |
| CKO_02669 | surE | CKO_02669 | CKO_04105 | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.926 |
| CKO_03267 | CKO_00208 | CKO_03267 | CKO_00208 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.996 |
| CKO_03267 | CKO_02669 | CKO_03267 | CKO_02669 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family. | 0.900 |
| CKO_03267 | CKO_03396 | CKO_03267 | CKO_03396 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; KEGG: stm:STM4580.S 1.5e-217 nadR; nicotinamide-nucleotide adenylyltransferase K00952:K06210:K06211; COG: COG3172 Predicted ATPase/kinase involved in NAD metabolism; Psort location: Cytoplasmic, score:8.96. | 0.931 |
| CKO_03267 | CKO_04051 | CKO_03267 | CKO_04051 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.920 |
| CKO_03267 | CKO_04136 | CKO_03267 | CKO_04136 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; KEGG: pha:PSHAa0740 1.5e-59 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; COG: COG1694 Predicted pyrophosphatase; Psort location: Cytoplasmic, score:8.96. | 0.903 |
| CKO_03267 | nadA | CKO_03267 | CKO_02390 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.996 |
| CKO_03267 | nadD | CKO_03267 | CKO_02517 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.929 |
| CKO_03267 | nudC | CKO_03267 | CKO_02990 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; KEGG: ssn:SSO_4169 1.2e-135 yjaD; hypothetical protein K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score:8.96. | 0.901 |
| CKO_03267 | pncB | CKO_03267 | CKO_02134 | Hypothetical protein; KEGG: spt:SPA0149 3.2e-142 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score:8.96; Belongs to the NadC/ModD family. | Hypothetical protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.939 |