| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_04102 | apaG | CKO_04102 | CKO_03330 | Hypothetical protein; KEGG: eci:UTI89_C3250 1.3e-44 ygeR; hypothetical lipoprotein YgeR precursor; COG: COG0739 Membrane proteins related to metalloendopeptidases. | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | 0.413 |
| CKO_04102 | lptD | CKO_04102 | CKO_03326 | Hypothetical protein; KEGG: eci:UTI89_C3250 1.3e-44 ygeR; hypothetical lipoprotein YgeR precursor; COG: COG0739 Membrane proteins related to metalloendopeptidases. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.534 |
| apaG | CKO_04102 | CKO_03330 | CKO_04102 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; KEGG: eci:UTI89_C3250 1.3e-44 ygeR; hypothetical lipoprotein YgeR precursor; COG: COG0739 Membrane proteins related to metalloendopeptidases. | 0.413 |
| apaG | apaH | CKO_03330 | CKO_03331 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.907 |
| apaG | djlA | CKO_03330 | CKO_03325 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.449 |
| apaG | lptD | CKO_03330 | CKO_03326 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.707 |
| apaG | pdxA | CKO_03330 | CKO_03328 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.894 |
| apaG | rsmA | CKO_03330 | CKO_03329 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.979 |
| apaG | surA | CKO_03330 | CKO_03327 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.896 |
| apaH | apaG | CKO_03331 | CKO_03330 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | 0.907 |
| apaH | lptD | CKO_03331 | CKO_03326 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.494 |
| apaH | pdxA | CKO_03331 | CKO_03328 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.557 |
| apaH | rsmA | CKO_03331 | CKO_03329 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.709 |
| apaH | surA | CKO_03331 | CKO_03327 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.762 |
| djlA | apaG | CKO_03325 | CKO_03330 | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | 0.449 |
| djlA | lptD | CKO_03325 | CKO_03326 | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.684 |
| djlA | pdxA | CKO_03325 | CKO_03328 | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Hypothetical protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.533 |
| djlA | rsmA | CKO_03325 | CKO_03329 | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.449 |
| djlA | surA | CKO_03325 | CKO_03327 | Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.626 |
| lptD | CKO_04102 | CKO_03326 | CKO_04102 | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Hypothetical protein; KEGG: eci:UTI89_C3250 1.3e-44 ygeR; hypothetical lipoprotein YgeR precursor; COG: COG0739 Membrane proteins related to metalloendopeptidases. | 0.534 |
