node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKO_02473 | apaH | CKO_02473 | CKO_03331 | Hypothetical protein; KEGG: ecc:c0773 3.8e-123 ybfF; putative esterase/lipase YbfF; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.766 |
CKO_02907 | apaH | CKO_02907 | CKO_03331 | COG: COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.928 |
CKO_02907 | rapA | CKO_02907 | CKO_03323 | COG: COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein. | Hypothetical protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.932 |
CKO_03625 | apaH | CKO_03625 | CKO_03331 | Hypothetical protein; KEGG: eci:UTI89_C4816 4.6e-104 fklB; FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (a rotamase) K03773; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: OuterMembrane, score:9.92. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.793 |
CKO_04375 | apaH | CKO_04375 | CKO_03331 | Hypothetical protein; KEGG: bur:Bcep18194_C7479 2.5e-128 alpha/beta hydrolase K00433; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.766 |
CKO_04753 | apaH | CKO_04753 | CKO_03331 | Hypothetical protein; KEGG: stm:STM3453 9.0e-131 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: Periplasmic, score:10.00. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.793 |
apaG | apaH | CKO_03330 | CKO_03331 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.886 |
apaG | rsmA | CKO_03330 | CKO_03329 | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.972 |
apaH | CKO_02473 | CKO_03331 | CKO_02473 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; KEGG: ecc:c0773 3.8e-123 ybfF; putative esterase/lipase YbfF; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.766 |
apaH | CKO_02907 | CKO_03331 | CKO_02907 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | COG: COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein. | 0.928 |
apaH | CKO_03625 | CKO_03331 | CKO_03625 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; KEGG: eci:UTI89_C4816 4.6e-104 fklB; FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (a rotamase) K03773; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: OuterMembrane, score:9.92. | 0.793 |
apaH | CKO_04375 | CKO_03331 | CKO_04375 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; KEGG: bur:Bcep18194_C7479 2.5e-128 alpha/beta hydrolase K00433; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.766 |
apaH | CKO_04753 | CKO_03331 | CKO_04753 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; KEGG: stm:STM3453 9.0e-131 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: Periplasmic, score:10.00. | 0.793 |
apaH | apaG | CKO_03331 | CKO_03330 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. | 0.886 |
apaH | bioH | CKO_03331 | CKO_04834 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.766 |
apaH | menH | CKO_03331 | CKO_00527 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.766 |
apaH | rapA | CKO_03331 | CKO_03323 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.732 |
apaH | rsmA | CKO_03331 | CKO_03329 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.740 |
bioH | apaH | CKO_04834 | CKO_03331 | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.766 |
menH | apaH | CKO_00527 | CKO_03331 | Hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.766 |