STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apaHHypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (282 aa)    
Predicted Functional Partners:
CKO_02907
COG: COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein.
   
 0.928
apaG
COG: COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport.
  
  
 0.886
CKO_03625
Hypothetical protein; KEGG: eci:UTI89_C4816 4.6e-104 fklB; FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (a rotamase) K03773; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: OuterMembrane, score:9.92.
    
 
 0.793
CKO_04753
Hypothetical protein; KEGG: stm:STM3453 9.0e-131 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: Periplasmic, score:10.00.
    
 
 0.793
menH
Hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
    
 0.766
CKO_02473
Hypothetical protein; KEGG: ecc:c0773 3.8e-123 ybfF; putative esterase/lipase YbfF; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
 0.766
CKO_04375
Hypothetical protein; KEGG: bur:Bcep18194_C7479 2.5e-128 alpha/beta hydrolase K00433; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
 0.766
bioH
Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
    
 0.766
rsmA
Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.740
rapA
Hypothetical protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 
 0.732
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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