close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
caiBHypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. (400 aa)    
Predicted Functional Partners:
caiA
Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family.
 
 
 0.963
caiC
Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine.
 
  
 0.915
caiD
Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
 
 
 0.912
fixA
Hypothetical protein; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 
 
 
 0.845
CKO_03340
Hypothetical protein; KEGG: fnu:FN1424 3.4e-26 acyl-CoA dehydrogenase, short-chain specific K00248; COG: COG2025 Electron transfer flavoprotein, alpha subunit.
 
   
 0.837
CKO_03338
Hypothetical protein; Could be a 3Fe-4S cluster-containing protein.
 
     0.802
CKO_03339
Hypothetical protein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.
 
   
 0.800
caiT
Hypothetical protein; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines.
 
   
 0.782
CKO_03337
Hypothetical protein; KEGG: cal:orf19.4384 1.2e-15 HXT10; fructose symporter K01804; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
     0.746
aes
Hypothetical protein; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity.
 
    0.709
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.