| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00943 | caiE | CKO_00943 | CKO_03348 | Hypothetical protein; KEGG: aha:AHA_2602 3.5e-136 dihydroorotase K01465; COG: COG0044 Dihydroorotase and related cyclic amidohydrolases; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.431 |
| CKO_03241 | caiE | CKO_03241 | CKO_03348 | Hypothetical protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.708 |
| caiA | caiB | CKO_03344 | CKO_03345 | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | 0.963 |
| caiA | caiC | CKO_03344 | CKO_03346 | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.880 |
| caiA | caiD | CKO_03344 | CKO_03347 | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.978 |
| caiA | caiE | CKO_03344 | CKO_03348 | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.403 |
| caiB | caiA | CKO_03345 | CKO_03344 | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.963 |
| caiB | caiC | CKO_03345 | CKO_03346 | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.915 |
| caiB | caiD | CKO_03345 | CKO_03347 | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.912 |
| caiB | caiE | CKO_03345 | CKO_03348 | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.529 |
| caiC | caiA | CKO_03346 | CKO_03344 | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.880 |
| caiC | caiB | CKO_03346 | CKO_03345 | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | 0.915 |
| caiC | caiD | CKO_03346 | CKO_03347 | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.932 |
| caiC | caiE | CKO_03346 | CKO_03348 | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.513 |
| caiD | caiA | CKO_03347 | CKO_03344 | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.978 |
| caiD | caiB | CKO_03347 | CKO_03345 | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | 0.912 |
| caiD | caiC | CKO_03347 | CKO_03346 | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.932 |
| caiD | caiE | CKO_03347 | CKO_03348 | Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.658 |
| caiE | CKO_00943 | CKO_03348 | CKO_00943 | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | Hypothetical protein; KEGG: aha:AHA_2602 3.5e-136 dihydroorotase K01465; COG: COG0044 Dihydroorotase and related cyclic amidohydrolases; Psort location: Cytoplasmic, score:8.96. | 0.431 |
| caiE | CKO_03241 | CKO_03348 | CKO_03241 | Hypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | Hypothetical protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.708 |