Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
caiEHypothetical protein; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. (197 aa)    
Predicted Functional Partners:
CKO_03241
Hypothetical protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
    
 
 0.710
caiD
Hypothetical protein; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
  
  
 0.681
caiB
Hypothetical protein; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily.
 
   
 0.551
caiC
Hypothetical protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine.
     
 0.535
CKO_00943
Hypothetical protein; KEGG: aha:AHA_2602 3.5e-136 dihydroorotase K01465; COG: COG0044 Dihydroorotase and related cyclic amidohydrolases; Psort location: Cytoplasmic, score:8.96.
  
  
 0.468
caiA
Hypothetical protein; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family.
 
   
 0.420
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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