STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03358Hypothetical protein; KEGG: reu:Reut_B5809 7.3e-65 5-carboxymethyl-2-hydroxymuconate delta-isomerase K01826; COG: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); Psort location: Cytoplasmic, score:8.96. (295 aa)    
Predicted Functional Partners:
CKO_03359
Hypothetical protein; Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system). Belongs to the sodium:citrate (SCF) symporter family.
 
     0.856
CKO_03362
Hypothetical protein; KEGG: btl:BALH_0517 1.4e-20 response regulator; COG: COG4565 Response regulator of citrate/malate metabolism; Psort location: Cytoplasmic, score:8.96.
 
     0.588
CKO_03361
Hypothetical protein; KEGG: eca:ECA2577 1.1e-164 citA; two-component sensor kinase K07700; COG: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; Psort location: CytoplasmicMembrane, score:9.99.
 
     0.566
garL
Hypothetical protein; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
  
  
 0.540
CKO_03360
Hypothetical protein.
       0.534
gshA
Hypothetical protein; KEGG: spt:SPA2677 1.2e-270 gshA; gamma-glutamylcysteine synthetase K01919; COG: COG2918 Gamma-glutamylcysteine synthetase; Psort location: Cytoplasmic, score:8.96; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
   
    0.480
rihC
Hypothetical protein; Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
       0.478
CKO_01318
Hypothetical protein; KEGG: stm:STM1749 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.431
CKO_03919
Hypothetical protein; KEGG: ecj:JW2580 5.1e-192 pheA; fused chorismate mutase P and prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.97.
     
 0.404
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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