STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSHypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)    
Predicted Functional Partners:
proS
Hypothetical protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
 0.986
leuS
Hypothetical protein; KEGG: ecc:c0733 0. leuS; leucyl-tRNA synthetase K01869; COG: COG0495 Leucyl-tRNA synthetase; Psort location: Cytoplasmic, score:9.26; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
0.972
argS
Hypothetical protein; KEGG: eco:b1876 1.0e-296 argS, lov; arginine tRNA synthetase K01887; COG: COG0018 Arginyl-tRNA synthetase; Psort location: Cytoplasmic, score:9.97.
  
 0.945
pheT
Hypothetical protein; KEGG: ecp:ECP_1661 0. phenylalanyl-tRNA synthetase beta chain K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score:9.97.
  
 
 0.943
lspA
Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
  
 0.939
metG
Hypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
0.923
valS
Hypothetical protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
 
0.920
lysS
Hypothetical protein; KEGG: eco:b2890 5.8e-262 lysS, asuD, herC; lysine tRNA synthetase, constitutive K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score:10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 0.920
glyS
Hypothetical protein; KEGG: ecc:c4378 0. glyS; glycyl-tRNA synthetase beta chain K01879; COG: COG0751 Glycyl-tRNA synthetase, beta subunit; Psort location: Cytoplasmic, score:8.96.
 
  
 0.905
CKO_01421
Hypothetical protein; COG: NOG22391 non supervised orthologous group.
  
 0.891
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.