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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpRHypothetical protein; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (99 aa)    
Predicted Functional Partners:
CKO_00214
Hypothetical protein; KEGG: ecp:ECP_2570 5.0e-169 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the peptidase S26 family.
   
    0.847
CKO_04894
COG: COG3776 Predicted membrane protein.
  
    0.803
matP
Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.770
CKO_01169
COG: COG3140 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0181 family.
  
     0.728
mukE
Hypothetical protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.706
CKO_02034
Hypothetical protein; KEGG: vfi:VFA0083 2.8e-08 ynfI; anaerobic dimethyl sulfoxide reductase chain YnfI K00397; COG: COG3381 Uncharacterized component of anaerobic dehydrogenases.
  
    0.697
CKO_03249
COG: COG3112 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0231 family.
  
     0.694
mukF
Hypothetical protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.689
CKO_01950
Hypothetical protein; KEGG: sec:SC1158 5.2e-80 ycfN; putative cytoplasmic protein K07251; COG: COG0510 Predicted choline kinase involved in LPS biosynthesis; Psort location: Cytoplasmic, score:8.96.
  
     0.669
CKO_04333
Hypothetical protein; COG: NOG06291 non supervised orthologous group.
  
     0.665
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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