Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_03419Hypothetical protein; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)    
Predicted Functional Partners:
CKO_03421
Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
  
 0.962
CKO_03418
Hypothetical protein; KEGG: spt:SPA4373 3.0e-107 yjjG; hypothetical protein K08723; COG: COG1011 Predicted hydrolase (HAD superfamily).
  
    0.903
prfC
Hypothetical protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
  
  
 0.780
rsmC
Hypothetical protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
  
    0.636
CKO_01173
KEGG: ecp:ECP_1750 1.3e-108 hypothetical protease YeaZ K01423; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Extracellular, score:9.71.
 
 
 0.596
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
 
   
 0.551
CKO_03422
Hypothetical protein.
       0.517
CKO_03908
Hypothetical protein; KEGG: eco:b4012 9.4e-65 yjaB; hypothetical protein K03827; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
  
   
 0.487
smpB
Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.476
CKO_04551
Hypothetical protein; KEGG: sec:SC3213 7.7e-86 yhbS; putative ABC superfamily (membrane) transport protein K03824; COG: COG3153 Predicted acetyltransferase; Psort location: Cytoplasmic, score:8.96.
  
  
 0.472
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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