close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03439Hypothetical protein; COG: NOG12172 non supervised orthologous group. (163 aa)    
Predicted Functional Partners:
CKO_03438
Hypothetical protein; KEGG: spi:MGAS10750_Spy1680 2.7e-12 replicative DNA helicase K01529; COG: COG1484 DNA replication protein.
 
    0.749
CKO_02304
COG: COG3637 Opacity protein and related surface antigens; Psort location: OuterMembrane, score:10.00.
  
     0.743
mzrA
Hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.733
CKO_01127
Hypothetical protein; COG: NOG09766 non supervised orthologous group.
  
     0.716
CKO_02102
COG: COG3110 Uncharacterized protein conserved in bacteria; Belongs to the UPF0319 family.
  
     0.705
aaeX
Hypothetical protein; COG: NOG13538 non supervised orthologous group.
  
     0.698
CKO_02787
Hypothetical protein; COG: NOG17162 non supervised orthologous group.
  
     0.683
CKO_01764
Hypothetical protein; COG: NOG09763 non supervised orthologous group.
  
     0.666
psiE
COG: COG3223 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.46.
  
     0.655
CKO_00260
Hypothetical protein; COG: NOG06208 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.654
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.