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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03470Hypothetical protein; KEGG: plu:plu0338 2.7e-193 dcm; DNA-cytosine methyltransferase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score:8.96. (474 aa)    
Predicted Functional Partners:
metK
Hypothetical protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.928
CKO_00981
Hypothetical protein; KEGG: stm:STM1992 1.4e-228 dcm; DNA cytosine methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score:8.96.
  
  
 
0.901
mtnN
Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
    
  0.901
speD
Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
     
  0.900
CKO_00982
Hypothetical protein; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.806
CKO_03469
Hypothetical protein; KEGG: nme:NMB1289 1.9e-50 type II restriction enzyme, putative K01155; COG: NOG14036 non supervised orthologous group.
 
   
 0.795
CKO_03471
Hypothetical protein.
       0.773
CKO_01169
COG: COG3140 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0181 family.
  
     0.494
CKO_01754
Hypothetical protein; COG: COG1988 Predicted membrane-bound metal-dependent hydrolases.
   
    0.480
CKO_03472
Hypothetical protein; KEGG: chu:CHU_1556 4.2e-11 DNA helicase K01529; COG: COG1112 Superfamily I DNA and RNA helicases and helicase subunits.
       0.422
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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