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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03517Hypothetical protein; COG: NOG11714 non supervised orthologous group. (410 aa)    
Predicted Functional Partners:
CKO_03516
Hypothetical protein.
  
    0.798
recC
Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]
  
 
 0.765
CKO_00047
Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]
  
 
 0.725
CKO_00161
Hypothetical protein; KEGG: sec:SC3857 0. recQ; ATP-dependent DNA helicase K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score:8.96.
  
 
 0.689
CKO_04373
COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: Extracellular, score:9.71.
  
     0.674
CKO_02105
Hypothetical protein; KEGG: eci:UTI89_C1028 0. helD; DNA helicase IV K03658; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score:8.96.
  
 
 0.668
recB
Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]
  
 
 0.668
CKO_01856
Hypothetical protein; KEGG: chu:CHU_1335 4.1e-09 CHU large protein; endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238; COG: COG5492 Bacterial surface proteins containing Ig-like domains.
  
     0.636
CKO_00300
Hypothetical protein; KEGG: nwi:Nwi_1293 6.1e-13 integrase, catalytic region K00986; COG: COG2801 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score:8.96.
  
     0.559
CKO_01269
Hypothetical protein; KEGG: spz:M5005_Spy_1700 1.2e-06 acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score:8.96.
  
     0.544
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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