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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03572Hypothetical protein; KEGG: stm:STM4453 2.1e-282 treC; trehalose-6-phosphate hydrolase K01226; COG: COG0366 Glycosidases; Psort location: Cytoplasmic, score:9.97. (551 aa)    
Predicted Functional Partners:
CKO_03571
Hypothetical protein; KEGG: spt:SPA4255 8.2e-240 treB; trehalose-specific IIBC component of PTS system K02818:K02819; COG: COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.998
CKO_01053
Hypothetical protein; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
  
 0.920
otsA
Hypothetical protein; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
  
 
 0.918
CKO_00028
Hypothetical protein; KEGG: sdy:SDY_4168 2.9e-221 putative 6-phospho-beta-glucosidase K01222; COG: COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; Psort location: Cytoplasmic, score:8.96.
  
  
 0.917
CKO_00375
Hypothetical protein; KEGG: stt:t0424 4.9e-84 crr; glucose-specific IIA component of PTS system K02777; COG: COG2190 Phosphotransferase system IIA components; Psort location: Cytoplasmic, score:10.00.
  
 
 0.911
treA
Hypothetical protein; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.
   
 
 0.907
treF
Hypothetical protein; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
   
 
 0.907
CKO_02945
Hypothetical protein; KEGG: ecp:ECP_2752 1.0e-223 PTS system, sucrose-specific IIBC component K02809:K02810; COG: COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Psort location: CytoplasmicMembrane, score:10.00.
 
  
 0.792
CKO_03569
Hypothetical protein; KEGG: efa:EF1922 9.4e-07 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score:9.26.
 
  
 0.700
CKO_02485
Hypothetical protein; KEGG: spt:SPA2056 0. nagE; pts system, N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; COG: COG2190 Phosphotransferase system IIA components; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.673
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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