STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_03803Hypothetical protein; KEGG: ecj:JW4040 4.1e-300 fdhF; formate dehydrogenase-H, selenopolypeptide subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (559 aa)    
Predicted Functional Partners:
CKO_04076
Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96.
 
 0.985
CKO_03800
Hypothetical protein; KEGG: stm:STM4285 1.7e-72 fdhF; formate dehydrogenase K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44.
 
     0.976
cysJ
Hypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.871
CKO_04077
Hypothetical protein; KEGG: eci:UTI89_C3085 8.3e-144 hycD; membrane-spanning protein of formate hydrogenase; COG: COG0650 Formate hydrogenlyase subunit 4; Psort location: CytoplasmicMembrane, score:10.00.
  
 0.846
CKO_04080
Hypothetical protein; KEGG: eci:UTI89_C3087 2.3e-86 hycB; formate hydrogenlyase subunit 2; COG: COG1142 Fe-S-cluster-containing hydrogenase components 2; Psort location: Cytoplasmic, score:8.96.
 
 
 0.845
fdhD
Hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 0.822
CKO_00325
Hypothetical protein; KEGG: eci:UTI89_C2794 1.1e-226 aegA, yffG; putative oxidoreductase Fe-S subunit K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.97.
 
 
 0.817
CKO_00512
Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
 
 
 0.810
CKO_04074
Hypothetical protein; KEGG: eci:UTI89_C3082 1.6e-131 hycG; formate hydrogenlyase subunit 7; COG: COG3260 Ni,Fe-hydrogenase III small subunit; Psort location: Cytoplasmic, score:8.96.
 
 
 0.781
CKO_00511
Hypothetical protein; KEGG: sty:STY2555 2.2e-88 nuoE; NADH dehydrogenase I chain E K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score:9.26.
  
 
 0.780
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.