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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lhgDHypothetical protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family. (422 aa)    
Predicted Functional Partners:
glaH
Hypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
 
 
 0.998
CKO_04009
Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.840
CKO_04008
Hypothetical protein; KEGG: stm:STM2791 1.7e-239 gabD; succinate-semialdehyde dehydrogenase I K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26.
  
  
 0.790
CKO_04011
Hypothetical protein; KEGG: msm:MSMEG_3400 4.3e-06 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators.
 
  
 0.710
CKO_04005
Hypothetical protein.
       0.505
CKO_02439
Hypothetical protein; KEGG: sec:SC0736 1.7e-225 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
  
  
 0.486
CKO_02829
Hypothetical protein; KEGG: ecp:ECP_0408 9.0e-202 2-methylcitrate synthase K01659; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
  
  
 0.486
CKO_01425
Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
  
  
 0.478
CKO_04620
Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96.
  
  
 0.475
CKO_04010
Hypothetical protein; KEGG: eci:UTI89_C0120 2.2e-72 aroP; aromatic amino acid transport protein AroP K03293; COG: COG1113 Gamma-aminobutyrate permease and related permeases; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.474
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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