Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_04010Hypothetical protein; KEGG: eci:UTI89_C0120 2.2e-72 aroP; aromatic amino acid transport protein AroP K03293; COG: COG1113 Gamma-aminobutyrate permease and related permeases; Psort location: CytoplasmicMembrane, score:10.00. (446 aa)    
Predicted Functional Partners:
CKO_04011
Hypothetical protein; KEGG: msm:MSMEG_3400 4.3e-06 glutamyl-tRNA(Gln) amidotransferase subunit A K01957; COG: COG1802 Transcriptional regulators.
     
 0.725
CKO_04009
Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.707
lhgD
Hypothetical protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family.
  
  
 0.496
CKO_04008
Hypothetical protein; KEGG: stm:STM2791 1.7e-239 gabD; succinate-semialdehyde dehydrogenase I K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26.
  
  
 0.480
glaH
Hypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
  
 0.436
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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