close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04034Hypothetical protein; COG: COG1566 Multidrug resistance efflux pump. (399 aa)    
Predicted Functional Partners:
CKO_04035
Hypothetical protein; KEGG: sgl:SG1466 1.5e-06 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.987
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.904
CKO_00657
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.857
CKO_02835
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.847
CKO_01443
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.838
CKO_02614
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.835
mdtD
Hypothetical protein; KEGG: sgl:SG1466 6.1e-08 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.769
CKO_00094
Hypothetical protein; KEGG: sgl:SG1466 2.2e-08 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.756
CKO_04033
Hypothetical protein; COG: COG1846 Transcriptional regulators; Psort location: Cytoplasmic, score:9.97.
 
  
 0.744
CKO_04427
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
  
 
 0.696
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.