Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04034Hypothetical protein; COG: COG1566 Multidrug resistance efflux pump. (399 aa)    
Predicted Functional Partners:
CKO_04035
Hypothetical protein; KEGG: sgl:SG1466 1.5e-06 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.995
CKO_04427
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
  
 
 0.909
CKO_00657
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.896
CKO_02835
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.879
CKO_01443
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.872
CKO_02614
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.870
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.866
mdtD
Hypothetical protein; KEGG: sgl:SG1466 6.1e-08 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.853
CKO_00094
Hypothetical protein; KEGG: sgl:SG1466 2.2e-08 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.844
CKO_02598
Hypothetical protein; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.797
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.