STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
norRHypothetical protein; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. (506 aa)    
Predicted Functional Partners:
CKO_04605
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.822
norV
Hypothetical protein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
 
   
 0.753
norW
Hypothetical protein; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.
 
   
 0.664
CKO_03790
Hypothetical protein; KEGG: psp:PSPPH_3276 1.4e-71 sensory box sensor histidine kinase/response regulator; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 
 0.625
CKO_04614
Hypothetical protein; KEGG: sec:SC3266 0. arcB; aerobic respiration control sensor protein K07648; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.97.
   
 
 0.602
CKO_04139
Hypothetical protein; KEGG: spt:SPA2823 0. barA; sensor protein; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.99.
   
 
 0.478
CKO_00437
Hypothetical protein; KEGG: eci:UTI89_C1702 2.7e-177 hypothetical protein; COG: COG2199 FOG: GGDEF domain; Psort location: CytoplasmicMembrane, score:7.88.
   
 
 0.477
CKO_00712
Hypothetical protein; KEGG: eci:UTI89_C2343 0. yegE; putative sensor-type protein; COG: COG2199 FOG: GGDEF domain; Psort location: CytoplasmicMembrane, score:10.00.
   
 
 0.477
hmp
Hypothetical protein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
     
 0.465
CKO_04620
Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96.
     
 0.444
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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