Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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norVHypothetical protein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (482 aa)    
Predicted Functional Partners:
norW
Hypothetical protein; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.
   
 0.993
CKO_01293
Hypothetical protein; KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.26; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.981
CKO_04789
Hypothetical protein; KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: Cytoplasmic, score:9.97; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.977
hcp
Hypothetical protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
   
 0.826
CKO_01425
Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
 
  
 0.813
norR
Hypothetical protein; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.
 
   
 0.773
CKO_01046
Hypothetical protein; Iron-storage protein.
 
  
 0.725
CKO_01042
Hypothetical protein; Iron-storage protein.
 
  
 0.716
CKO_02554
Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.714
CKO_02758
Hypothetical protein; KEGG: stm:STM0402 2.0e-101 putative thiol - alkyl hydroperoxide reductase K03386; COG: COG0450 Peroxiredoxin; Psort location: Cytoplasmic, score:9.97.
  
  
 0.714
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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