close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04274COG: COG3079 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0149 family. (194 aa)    
Predicted Functional Partners:
CKO_04272
Hypothetical protein; KEGG: sbo:SBO_3085 2.0e-181 ubiH; UbiH K03185; COG: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
   
 0.862
CKO_04273
Hypothetical protein; KEGG: sec:SC2999 4.9e-226 pepP; proline aminopeptidase P II K01262; COG: COG0006 Xaa-Pro aminopeptidase.
     
 0.821
rcsF
Hypothetical protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.757
CKO_00273
COG: COG2976 Uncharacterized protein conserved in bacteria.
  
     0.738
CKO_04193
Hypothetical protein; COG: COG2165 Type II secretory pathway, pseudopilin PulG.
  
     0.735
CKO_02109
Hypothetical protein; COG: COG3070 Regulator of competence-specific genes.
  
     0.718
CKO_03245
Hypothetical protein; COG: NOG09835 non supervised orthologous group.
  
     0.692
CKO_02229
Hypothetical protein; KEGG: rme:Rmet_2422 0.0046 peptidase S1C, Do K04771; COG: COG3031 Type II secretory pathway, component PulC; Psort location: CytoplasmicMembrane, score:9.82.
  
     0.680
lptE
Hypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
  
     0.673
zapA
Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
  
 0.671
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.