Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04401Hypothetical protein; COG: COG0811 Biopolymer transport proteins; Psort location: CytoplasmicMembrane, score:10.00. (239 aa)    
Predicted Functional Partners:
CKO_04400
Hypothetical protein; COG: COG0848 Biopolymer transport protein.
 
 
 0.999
CKO_01329
Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.991
tolR
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.984
CKO_00040
COG: COG0810 Periplasmic protein TonB, links inner and outer membranes; Psort location: CytoplasmicMembrane, score:8.02.
 
 
 0.929
CKO_03429
Hypothetical protein; KEGG: gbe:GbCGDNIH1_2380 0.00064 ferric hydroxamate reductase FhuF K00521; COG: COG4114 Uncharacterized Fe-S protein; Psort location: Cytoplasmic, score:8.96.
   
  
 0.901
tolB
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.896
CKO_03218
Hypothetical protein; KEGG: sgl:SG1838 2.4e-06 putative mannonate dehydratase K01686; COG: COG1629 Outer membrane receptor proteins, mostly Fe transport; Psort location: OuterMembrane, score:10.00.
 
  
 0.875
CKO_02569
Hypothetical protein; COG: COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component; Psort location: Periplasmic, score:9.76.
   
  
 0.818
pal
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.683
CKO_02566
Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96.
   
  
 0.655
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (24%) [HD]